← Back to dashboard

Liver enzymes and oxidative stress

Detox & Antioxidants

Your liver uses these enzymes to break down caffeine, medications, alcohol, and toxins so your body can wash them out.

CYP1A2 · rs762551

*1F

Low-priority conversation
Your genotypeC / CTypical (no variant copies)
Chromosomechr 15Reference C · Variant A
Evidence
Level B
Reviewed 2025-01
In plain language
CYP1A2 breaks down caffeine. AA is 'fast,' AC is intermediate, CC is 'slow.'
What this may suggest
Slow metabolizers can feel jittery, sleep poorly, or feel heart-pounding from coffee even in the morning.
What this does NOT tell us
Sensitivity also depends on sleep, hormones, and other medications.
Simple food & lifestyle ideas
  • If slow, try half-caf or cut caffeine after noon.

Questions for your clinician

  • “Given my results, is my caffeine intake reasonable for me?”
GSTP1 · rs1695

I105V

Could be a problem
Your genotypeA / GOne variant copy
Chromosomechr 11Reference A · Variant G
Evidence
Level C
Reviewed 2025-01
In plain language
GSTP1 helps hitch a molecule called glutathione to toxins so your body can carry them out.
What this may suggest
The G version has slightly lower activity in lab studies.
What this does NOT tell us
Does not mean you 'can't detox.' Your liver has many overlapping enzymes.
Simple food & lifestyle ideas
  • Cruciferous vegetables (broccoli, arugula, cauliflower) help support glutathione naturally.
  • Whey protein, eggs, and garlic supply the raw materials.

Questions for your clinician

  • “Any lifestyle changes you'd suggest to support antioxidant status?”
SOD2 · rs4880

A16V

Could be a problem
Your genotypeC / TOne variant copy
Chromosomechr 6Reference C · Variant T
Evidence
Level C
Reviewed 2025-01
In plain language
SOD2 is a key antioxidant enzyme inside your cell's energy factories (mitochondria).
What this may suggest
Different versions may reach mitochondria more or less easily.
What this does NOT tell us
Not a health verdict.
Simple food & lifestyle ideas
  • Colorful plants (berries, greens, orange veggies) are natural antioxidants.
NQO1 · rs1800566

P187S

Low-priority conversation
Your genotypeG / GTypical (no variant copies)
Chromosomechr 16Reference G · Variant A
Evidence
Level C
Reviewed 2025-01
In plain language
NQO1 recycles antioxidants like CoQ10 and vitamin E.
What this may suggest
The A version has lower activity.
What this does NOT tell us
Not a diagnosis.
Simple food & lifestyle ideas
  • Foods rich in CoQ10 include fish, nuts, and olive oil.

What this chapter does NOT tell you

Your genes are one signal. Blood work, symptoms, family history, medications, and your daily life all matter more than any single result on this page. Bring these notes to a clinician who knows you — do not start, stop, or change medications or high-dose supplements based on this report alone.